746 research outputs found
SPACES FOR WHOM? : IDENTIFYING PARTICIPATORY STRATEGIES TO FOSTER STUDENTS\u27 SENSE OF BELONGING ON COMMUNITY COLLEGE CAMPUSES
In the United States, community colleges have served diverse student populations, including students of color and students with disabilities. While these colleges are celebrated for their access and affordability, student success is not guaranteed. As educators work to continuously improve course and program completion, students’ sense of belonging is critical. However, a review of scholarship from education, architecture, and planning revealed how students have navigated campuses that have not met their needs or reflected their experiences and have even been settings for discriminatory behaviors ranging from microaggressions to oppression. Recognizing the potential to increase sense of belonging through student participation and empowerment, this study used critical inquiry to determine how four community colleges recognized by the INSIGHT Into Diversity Higher Education Excellence in Diversity Award have promoted belongingness as they developed campus spaces. While interviews with college presidents and vice presidents revealed the will to engage students in campus building, none of the colleges achieved the highest levels of student participation during their most recent capital projects. Additionally, the study found that student participation occurred because of leaders’ choices, as formal structures to ensure student involvement were not evident. Finally, the study concludes with practical implications for colleges aiming to increase student belongingness and success as they invest in campus structures and features that will last for decades
RIVPACS database documentation. Final report
With the advent of the EU Water Framework Directive the concept of the 'reference condition' has become explicit within the legislative framework of the European Union. Reference condition has been established as a quality standard against which assessments of biological degradation must be compared. It is therefore essential that Member States can demonstrate that the biological datasets used to define their reference conditions meet the criteria of the WFD. The RIVPACS reference site dataset is therefore central to the definition of reference conditions for macroinvertebrates in streams and rivers in the United Kingdom.
Objectives of research:
• To establish the ownership of the RIVPACS reference site dataset
• To liaise with all stakeholders of the dataset to establish unhindered access to the RIVPACS reference site dataset for the UK agencies (in perpetuity)
• To deliver the RIVPACS reference site dataset to the UK agencies and to the public domain in a readily accessible database together will its accompanying physicochemical variables (both existing and newly collated as part of this project), historical and current anthropogenic stress data, and a range of calculated biotic indices.
Key findings and recommendations:
Ownership of the RIVPACS dataset resides with no single organization and several different organizations consider that they own different portions of the dataset. Formal permissions to release the dataset into the public domain have been obtained from all twelve extant organizations that have been identified as having funded various phases of RIVPACS research. In addition, CEH/NERC has also agreed to release the RIVPACS dataset to the public domain. Terms and conditions relating to the end use of the RIVPACS dataset have now been established. The RIVPACS database has been assembled in Microsoft® Access and can now be downloaded from the CEH web site. This report details the terms and conditions that apply to all end users of the database and it documents the tables given in the database, their structure and the origin of their data. A separate Pressure Data Analysis report describes the screening of the RIVPACS sites in terms of the current and emerging definitions of reference condition
Family meetings for older adults in intermediate care settings: the impact of patient cognitive impairment and other characteristics on shared decision making
"This is the peer reviewed version of the following article: [Milte CM, Ratcliffe J, Davies O, Whitehead C, Masters S, Crotty M. Family meetings for older adults in intermediate care settings: the impact of patient cognitive impairment and other characteristics on shared decision making. Health Expectations. 2015 Oct;18(5):1030-40. ], which has been published in final form at [http://dx.doi.org/10.1111/hex.12076]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms"BACKGROUND:
Clinicians, older adults and caregivers frequently meet to make decisions around treatment and lifestyle during an acute hospital admission. Patient age, psychological status and health locus of control (HLC) influence patient preference for consultation involvement and information but overall, a shared-decision-making (SDM) approach is favoured. However, it is not known whether these characteristics and the presence of cognitive impairment influence SDM competency during family meetings.
OBJECTIVE:
To describe meetings between older adults, caregivers and geriatricians in intermediate care and explore patient and meeting characteristics associated with a SDM communication style.
METHODS:
Fifty-nine family meetings involving geriatricians, patients in an intermediate care setting following an acute hospital admission and their caregivers were rated using the OPTION system for measuring clinician SDM behaviour. The geriatric depression scale and multidimensional HLC scale were completed by patients. The mini-mental state exam (MMSE) assessed patient's level of cognitive impairment.
RESULTS:
Meetings lasted 38 min (SD 13) and scored 41 (SD 17) of 100 on the OPTION scale. Nine (SD 2.2) topics were discussed during each meeting, and most were initiated by the geriatrician. Meeting length was an important determinant of OPTION score, with higher SDM competency displayed in longer meetings. Patient characteristics, including MMSE, HLC and depression did not explain SDM competency.
CONCLUSION:
Whilst SDM can be achieved during consultations frail older patients and their caregivers, an increased consultation time is a consequence of this approach
Proteomic resistance biomarkers for PI3K inhibitor in triple negative breast cancer patient-derived xenograft models
PI3K pathway activation is frequently observed in triple negative breast cancer (TNBC). However, single agent PI3K inhibitors have shown limited anti-tumor activity. To investigate biomarkers of response and resistance mechanisms, we tested 17 TNBC patient-derived xenograft (PDX) models representing diverse genomic backgrounds and varying degrees of PI3K pathway signaling activities for their tumor growth response to the pan-PI3K inhibitor, BKM120. Baseline and post-treatment PDX tumors were subjected to reverse phase protein array (RPPA) to identify protein markers associated with tumor growth response. While BKM120 consistently reduced PI3K pathway activity, as demonstrated by reduced levels of phosphorylated AKT, percentage tumor growth inhibition (%TGI) ranged from 35% in the least sensitive to 84% in the most sensitive model. Several biomarkers showed significant association with resistance, including elevated baseline levels of growth factor receptors (EGFR, pHER3 Y1197), PI3Kp85 regulatory subunit, anti-apoptotic protein BclXL, EMT (Vimentin, MMP9, IntegrinaV), NFKB pathway (IkappaB, RANKL), and intracellular signaling molecules including Caveolin, CBP, and KLF4, as well as treatment-induced increases in the levels of phosphorylated forms of Aurora kinases. Interestingly, increased AKT phosphorylation or PTEN loss at baseline were not significantly correlated to %TGI. These results provide important insights into biomarker development for PI3K inhibitors in TNBC
Exile Vol. XXV No. 1
PROSE
Friend by John Marshall
Visiting Relatives by Cynthia Lanning Hahn
The Mud Lane by Eloise Haveman
The Petrification of a Wild Sweet William Blossom by Melissa Simmons
ART
Three views of Granville by Scott Tryon (front cover)
untitled photos by Bogart and Jerry Brown
Landscape by Scott Tryon
Submissive Defiance by Bogart
Three things that Remain by Jerry Brown
back cover by Lindy Davies
POETRY
A Photographer Documents Her Death by Chris Gjessing
three Haiku by Eloise Haveman
Morning by Melissa Simmons
Granite Travel by Lisa Minacci
did you year? by Bob McLaughlin
he\u27s coming home again by Bob McLaughlin
David by Betsy Bates
Le Cafe de \u27lUnivers by Ann Leopard
untitled by John Marshall
The Last Ramona Poem (fat chance) by Lindy Davies
Mother Told Me not to Play Next Door by Ellen Cox
Poems of the Inconsequentials by Eloise Havema
What do children want from the BBC?: Children’s content and participatory environments in an age of citizen media
This collaborative research project was funded through the
AHRC/BBC Knowledge Exchange Programme’s pilot funding
call. The aim of this initiative is to develop a long-term strategic partnership, bringing together the arts and humanities research community with BBC staff to enable co-funded knowledge exchange in the form of collaborative research and development. The benefits from the outcomes and outputs of these projects should be of equal significance to both partners
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